Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 3/20 | 0.40 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100925 | 0.83 | NSD2 (0.46) | PREPNSD2FAPMEN1KMT2A | |
| SCHEMBL28540686 | 0.81 | NSD2 (0.44) | PREPNSD2FAPMEN1KMT2A | |
| SCHEMBL28535856 | 0.80 | KMT2A (0.49) | PREPNSD2FAPMEN1KMT2A | |
| SCHEMBL28530340 | 0.78 | NSD2 (0.42) | PREPNSD2FAPCNR2 | |
| SCHEMBL28540688 | 0.78 | NSD2 (0.45) | PREPNSD2FAP | |
| SCHEMBL31468412 | 0.76 | NR4A1 (0.52) | MEN1KMT2ACNR2 | |
| SCHEMBL827639 | 0.74 | MEN1 (0.47) | NSD2MEN1KMT2A | |
| SCHEMBL23193358 | 0.73 | NCF1 (0.50) | NSD2 | |
| SCHEMBL6824375 | 0.73 | ALDH1A1 (0.47) | PREPFAPMEN1KMT2A | |
| SCHEMBL1856898 | 0.73 | SLC6A2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467549-B | Quinoline-substituted chalcone compound, preparation method and application thereof | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |