Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 3/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100925 | 0.88 | NSD2 (0.46) | NSD2PREPFAPCCR1NCF1 | |
| SCHEMBL28535856 | 0.85 | KMT2A (0.49) | NSD2PREPFAPCCR1NCF1 | |
| SCHEMBL28540688 | 0.83 | NSD2 (0.45) | NSD2PREPFAPCCR1CYP1A2 | |
| SCHEMBL28530340 | 0.83 | NSD2 (0.42) | NSD2PREPFAPCCR1NCF1 | |
| SCHEMBL28535313 | 0.81 | PREP (0.46) | NSD2PREPFAPMEN1KMT2A | |
| SCHEMBL827639 | 0.79 | MEN1 (0.47) | NSD2NCF1PTPN1PTPN11NPC1 | |
| SCHEMBL23193358 | 0.78 | NCF1 (0.50) | NSD2NCF1PTPN1PTPN11NPC1 | |
| SCHEMBL6824375 | 0.78 | ALDH1A1 (0.47) | PREPFAPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL228713 | 0.77 | KDM4E (0.56) | NSD2NCF1NPC1ESR1TP53 | |
| SCHEMBL29375172 | 0.77 | KDM4E (0.56) | NSD2NCF1NPC1ESR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467549-B | Quinoline-substituted chalcone compound, preparation method and application thereof | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |