Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211316 | 0.83 | PTGS1 (0.43) | MAPTALDH1A1L3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL953114 | 0.82 | MAPT (0.56) | MAPTALDH1A1TSHRTRPA1L3MBTL1 | |
| SCHEMBL11205005 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL28533184 | 0.80 | L3MBTL1 (0.36) | MAPTALDH1A1L3MBTL1MAPK1TDP1 | |
| SCHEMBL4796278 | 0.73 | TSHR (0.38) | ALDH1A1TSHRTRPA1SMN1; SMN2MAPK1 | |
| SCHEMBL8793813 | 0.73 | L3MBTL1 (0.50) | MAPTALDH1A1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL1709986 | 0.73 | L3MBTL1 (0.50) | MAPTALDH1A1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL29700321 | 0.73 | L3MBTL1 (0.50) | MAPTALDH1A1TSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL9493266 | 0.72 | TSHR (0.46) | MAPTALDH1A1TSHRTRPA1L3MBTL1 | |
| SCHEMBL28515424 | 0.72 | TSHR (0.50) | MAPTALDH1A1TSHRTRPA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112472699-A | Combination methods for improving the therapeutic benefit of bisantrene and derivatives | 种族肿瘤学公司 | 2021-03-12 | — | — | CN | disclosed |