Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131271 | 0.83 | NPC1 (0.30) | NPC1RAB9A | |
| SCHEMBL26746816 | 0.83 | NPC1 (0.30) | NPC1RAB9A | |
| SCHEMBL21384323 | 0.83 | NPC1 (0.30) | NPC1RAB9A | |
| SCHEMBL21384320 | 0.83 | NPC1 (0.30) | NPC1RAB9A | |
| SCHEMBL21389491 | 0.81 | PPM1D (0.32) | PPM1DNPC1RAB9A | |
| SCHEMBL21383850 | 0.79 | KMT2A (0.34) | PPM1DNPC1 | |
| SCHEMBL30131252 | 0.73 | KEAP1 (0.44) | — | |
| SCHEMBL24796004 | 0.73 | FABP3 (0.32) | — | |
| SCHEMBL31737625 | 0.72 | LMNA (0.39) | PPM1DNPC1RAB9A | |
| SCHEMBL31513902 | 0.70 | PDE4A (0.36) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |