Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384320 | 1.00 | NPC1 (0.30) | NPC1RAB9ABUB1 | |
| SCHEMBL21384323 | 1.00 | NPC1 (0.30) | NPC1RAB9ABUB1 | |
| SCHEMBL21389491 | 0.88 | PPM1D (0.32) | NPC1RAB9A | |
| SCHEMBL28536009 | 0.86 | PLA2G7 (0.30) | — | |
| SCHEMBL21389115 | 0.86 | PLA2G7 (0.30) | — | |
| SCHEMBL28529851 | 0.86 | PLA2G7 (0.30) | — | |
| SCHEMBL28535386 | 0.83 | PPM1D (0.32) | NPC1RAB9A | |
| SCHEMBL21383850 | 0.80 | KMT2A (0.34) | NPC1 | |
| SCHEMBL7216001 | 0.75 | ALOX15 (0.39) | — | |
| SCHEMBL24796004 | 0.74 | FABP3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-11535660-B1 | Modulators of G-protein coupled receptors | Cannot Therapeutics, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | NPC1 1890/4885RAB9A 664/4885BUB1 3649/4885 |
| US-11535660-B1 | Modulators of G-protein coupled receptors | GIPR, GLP1R, GCGR | NPC1 1936/4885RAB9A 616/4885BUB1 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.