Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040459 | 0.78 | P2RX4 (0.41) | P2RX4KMT2AMEN1 | |
| SCHEMBL29380399 | 0.76 | BCHE (0.46) | P2RX4BCHE | |
| SCHEMBL5560408 | 0.76 | BCHE (0.46) | P2RX4BCHE | |
| SCHEMBL27766280 | 0.75 | DRD2 (0.37) | DRD2KMT2AMEN1BCHEEPHX2 | |
| SCHEMBL30809492 | 0.73 | P2RX4 (0.38) | P2RX4 | |
| SCHEMBL9420578 | 0.73 | TGM2 (0.37) | P2RX4 | |
| SCHEMBL29986227 | 0.72 | DRD2 (0.47) | DRD2KMT2AMEN1NFKB1NFKB2 | |
| SCHEMBL8472507 | 0.71 | P2RX4 (0.37) | P2RX4 | |
| SCHEMBL1862101 | 0.69 | DRD2 (0.40) | DRD2KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL3661398 | 0.69 | MAPK1 (0.50) | DRD2KMT2AMEN1BCHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-106257976-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-02-02 | — | — | CN | disclosed |