Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCKDK | O14874 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680455 | 0.78 | BCKDK (0.41) | BCKDKMPIMIFRAB9AKDM4E | |
| SCHEMBL28429478 | 0.77 | BCKDK (0.37) | BCKDKMPIMIFG6PDMTNR1A | |
| SCHEMBL14293108 | 0.75 | BCKDK (0.58) | BCKDKRAB9AKDM4EPTGS1MAOB | |
| SCHEMBL1255148 | 0.75 | BCKDK (0.58) | BCKDKRAB9AKDM4EPTGS1MAOB | |
| SCHEMBL16231302 | 0.74 | BCKDK (0.38) | BCKDKMPIMIFRAB9AKDM4E | |
| SCHEMBL12678220 | 0.74 | BCKDK (0.38) | BCKDKMPIMIFRAB9AKDM4E | |
| SCHEMBL29707472 | 0.74 | MPI (0.42) | BCKDKMPIMIFRAB9AKDM4E | |
| SCHEMBL3159924 | 0.74 | MPI (0.42) | BCKDKMPIMIFRAB9AKDM4E | |
| SCHEMBL28824192 | 0.72 | IDO1 (0.51) | BCKDKMPIMIFKDM4EG6PD | |
| SCHEMBL13659612 | 0.72 | BCKDK (0.54) | BCKDKRAB9AKDM4EPTGS1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107873031-B | Benzoxazinone derivatives and analogs thereof as modulators of TNF activity | UCB生物制药私人有限公司 | 2021-03-12 | — | — | CN | disclosed |