Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCKDK | O14874 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TLR3 | O15455 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659611 | 0.90 | BCKDK (0.68) | BCKDKRAB9AKDM4ESENP1TLR3 | |
| SCHEMBL31126911 | 0.85 | TRPM8 (0.42) | BCKDKRAB9AKDM4ETRPM8PTGS1 | |
| SCHEMBL1255148 | 0.83 | BCKDK (0.58) | BCKDKRAB9AKDM4ESENP1SMN1; SMN2 | |
| SCHEMBL14293108 | 0.83 | BCKDK (0.58) | BCKDKRAB9AKDM4ESENP1SMN1; SMN2 | |
| SCHEMBL13659606 | 0.80 | MCL1 (0.65) | RAB9AKDM4ESMN1; SMN2NPC1TP53 | |
| SCHEMBL13659636 | 0.78 | GPR35 (0.51) | BCKDKRAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL28965823 | 0.76 | BCKDK (0.45) | BCKDKRAB9AKDM4ESENP1TLR3 | |
| SCHEMBL13659630 | 0.76 | MCL1 (0.70) | BCKDKRAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13659633 | 0.72 | MCL1 (0.47) | BCKDKRAB9AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL12678220 | 0.72 | BCKDK (0.38) | BCKDKRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247513-A1 | BENZOTHIOPHENE COMPOUNDS HAVING ANTIINFECTIVE ACTIVITY | GENESOFT PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
| US-7329765-B2 | Benzothiophene compounds having antiinfective activity | GENESOFT PHARMACEUTICALS, INC. (US) | 2008-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247513-A1 | BENZOTHIOPHENE COMPOUNDS HAVING ANTIINFECTIVE ACTIVITY | TOP2A, TOP1, TOP2B | BCKDK 3231/4885RAB9A 4107/4885KDM4E 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.