Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flumetramide SCHEMBL258835 | 0.85 | PRKAB2 (0.43) | HTR1APARP1PARP2HTR2C | |
| Flumetramide SCHEMBL9576017 | 0.85 | PRKAB2 (0.43) | HTR1APARP1PARP2HTR2C | |
| SCHEMBL25177356 | 0.81 | DDB1 (0.40) | DDB1CRBN | |
| SCHEMBL25181459 | 0.80 | TSHR (0.44) | HTR1ADDB1CRBN | |
| SCHEMBL1760973 | 0.75 | HTR1A (0.68) | HTR1A | |
| SCHEMBL22053358 | 0.75 | HTR1A (0.68) | HTR1A | |
| SCHEMBL10242078 | 0.75 | HTR2C (0.41) | PARP1PARP2HTR2C | |
| SCHEMBL5021639 | 0.75 | HTR2C (0.41) | PARP1PARP2HTR2C | |
| Oxalic Acid SCHEMBL12520684 | 0.71 | HTR1A (0.59) | HTR1A | |
| SCHEMBL8352445 | 0.70 | TSHR (0.53) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |