Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535546 | 0.86 | KDM4E (0.50) | SMN1; SMN2LMNARAB9ATP53MAPT | |
| SCHEMBL28551931 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2LMNATP53MAPTTDP1 | |
| SCHEMBL28537502 | 0.78 | MAPT (0.47) | SMN1; SMN2LMNARAB9ATP53MAPT | |
| SCHEMBL28547674 | 0.77 | CFTR (0.44) | LMNAPOLBALDH1A1MAPK1KDM4E | |
| SCHEMBL28542045 | 0.77 | HSD11B1 (0.48) | LMNAKMT2APOLBALDH1A1MAPK1 | |
| SCHEMBL28546377 | 0.75 | MAPK1 (0.45) | SMN1; SMN2LMNATP53TDP1MEN1 | |
| SCHEMBL28542974 | 0.74 | TDP1 (0.40) | SMN1; SMN2LMNAMAPTTDP1MEN1 | |
| SCHEMBL28547606 | 0.74 | KMT2A (0.39) | SMN1; SMN2LMNAMAPTTDP1MEN1 | |
| SCHEMBL28537517 | 0.72 | KDM4E (0.44) | SMN1; SMN2LMNATP53MAPTMEN1 | |
| SCHEMBL28458600 | 0.69 | KDM4E (0.57) | SMN1; SMN2LMNATP53MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457263-A | Novel method for synthesizing aryl sulfone derivative | 桂林理工大学 | 2021-03-09 | — | — | CN | disclosed |