Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537502 | 0.90 | MAPT (0.47) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28542045 | 0.90 | HSD11B1 (0.48) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28547674 | 0.90 | CFTR (0.44) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28542974 | 0.87 | TDP1 (0.40) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28547606 | 0.86 | KMT2A (0.39) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28535538 | 0.86 | SMN1; SMN2 (0.38) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28551931 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1LMNANPSR1KMT2A | |
| SCHEMBL28546377 | 0.85 | MAPK1 (0.45) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28537517 | 0.85 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL31300308 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1HPGDMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457263-A | Novel method for synthesizing aryl sulfone derivative | 桂林理工大学 | 2021-03-09 | — | — | CN | disclosed |