Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873288 | 0.81 | — | — | |
| SCHEMBL18975587 | 0.79 | ALDH1A1 (0.36) | CYP1A2 | |
| SCHEMBL23343604 | 0.76 | GRM5 (0.51) | CYP1A2TDP1KDM4ESMN1; SMN2 | |
| SCHEMBL344121 | 0.74 | USP2 (0.41) | SMN1; SMN2 | |
| SCHEMBL23867770 | 0.74 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL28158154 | 0.71 | DRD3 (0.33) | — | |
| SCHEMBL18975880 | 0.71 | HPGD (0.47) | — | |
| SCHEMBL20994916 | 0.71 | USP30 (0.33) | CYP1A2 | |
| SCHEMBL9095169 | 0.68 | NOTUM (0.38) | NOTUMBPTFAURKACCNA2CDK2 | |
| SCHEMBL4420849 | 0.68 | GRM5 (0.55) | CYP1A2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149993-A | Pyrrolopyrimidine derivative compound, pharmaceutical composition and application thereof | 北京普祺医药科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-109867675-B | Pyrrolopyrimidine derivative compound, pharmaceutical composition and application thereof | 北京普祺医药科技有限公司 | 2021-01-19 | — | — | CN | disclosed |