Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | CPT1A | P50416 | 2/20 | 0.31 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433663 | 0.90 | MAPT (0.38) | PTPN2GPR6CPT1ACPT1BCPT2 | |
| SCHEMBL19433642 | 0.79 | GPR35 (0.40) | GPR35BCL2L1PTPN2CPT1ACPT1B | |
| SCHEMBL19433704 | 0.78 | NLRP3 (0.43) | GPR35 | |
| SCHEMBL19433680 | 0.78 | GPR35 (0.42) | GPR35BCL2L1PTPN2TBXAS1 | |
| SCHEMBL19433716 | 0.77 | GPR35 (0.39) | GPR35BCL2L1PTPN2 | |
| SCHEMBL19433589 | 0.76 | GPR35 (0.40) | GPR35BCL2L1PTPN2 | |
| SCHEMBL19433677 | 0.73 | GPR35 (0.40) | GPR35BCL2L1PTPN2 | |
| SCHEMBL19433655 | 0.72 | GPR119 (0.39) | CPT1ACPT1BCPT2 | |
| SCHEMBL19433683 | 0.71 | GPR35 (0.36) | GPR35BCL2L1PTPN2 | |
| SCHEMBL4830635 | 0.70 | GPR35 (0.50) | GPR35BCL2L1PTPN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001345-B | Heterocyclic derivatives and use thereof | 株式会社C&C新药研究所 | 2021-03-02 | — | — | CN | disclosed |