SCHEMBL28536189

SCHEMBL28536189

CCC(C)(C)C(=O)C(C)C(O)=S

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8463336 0.84 RIPK1 (0.32) RIPK1
SCHEMBL4053641 0.82 TP53 (0.33) RIPK1
SCHEMBL4799234 0.77 HSP90AA1 (0.31)
SCHEMBL29242539 0.74 CA1 (0.33)
SCHEMBL10044964 0.74 CYP1A2 (0.38) RIPK1
SCHEMBL18291780 0.71
SCHEMBL13829178 0.70 TSHR (0.31) RIPK1
SCHEMBL12060203 0.70 TSHR (0.31) RIPK1
SCHEMBL8988268 0.70 CHRM2 (0.31)
SCHEMBL11457365 0.70 RIPK1 (0.30) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109402085-B Recombinant strains, methods for synthesizing simvastatin, and related enzymes 中国科学院青岛生物能源与过程研究所 2021-02-12 CN disclosed