SCHEMBL10044964

SCHEMBL10044964

CCC(C)(C)C(=O)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
RIPK1 Q13546 14/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8463336 0.83 RIPK1 (0.32) RIPK1
SCHEMBL18893563 0.80 CYP1A2 (0.39) CYP1A2
SCHEMBL5138301 0.79 CYP1A2 (0.43) CYP1A2
SCHEMBL13829178 0.79 TSHR (0.31) RIPK1
SCHEMBL11457365 0.79 RIPK1 (0.30) RIPK1
SCHEMBL12060203 0.79 TSHR (0.31) RIPK1
SCHEMBL17482399 0.79 CYP1A2 (0.33) CYP1A2
SCHEMBL14341529 0.78 TSHR (0.33) RIPK1
SCHEMBL8463086 0.78 MMP8 (0.31) CYP1A2
SCHEMBL11430316 0.78 TSHR (0.31) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348388-A1 Highly Purified Batches Of Pharmaceutical Grade Migalastat And Methods Of Producing The Same AMICUS THERAPEUTICS, INC. (US) 2023-11-02 US disclosed
US-11802132-B2 Small molecules for inducing selective protein degradation and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-10-31 US disclosed
US-11802132-B2 Small molecules for inducing selective protein degradation and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2023-10-31 US disclosed
US-20230330254-A1 ANTI-GLP1R ANTIBODY-TETHERED DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2023-10-19 US disclosed
US-11685718-B2 Highly purified batches of pharmaceutical grade 1-deoxygalactonojirimycin compounds AMICUS THERAPEUTICS, INC. (US) 2023-06-27 US disclosed
WO-2022119792-A1 PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST EASTMAN CHEMICAL COMPANY (US) 2022-06-09 WO disclosed
US-20200407371-A1 SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2020-12-31 US disclosed
US-20180057505-A1 BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY VERTEX PHARMACEUTICALS INCORPORATED 2018-03-01 US disclosed
US-20170334815-A1 CATALYST AND METHOD FOR HYDROGENATION OF 1,3-CYCLOBUTANEDIKETONE COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-11-23 US disclosed
US-9770439-B2 Hepatitis C virus inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-09-26 US disclosed
US-20090191153-A1 OXIMYL MACROCYCLIC DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2009-07-30 US disclosed
US-20090191153-A1 OXIMYL MACROCYCLIC DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2009-07-30 US disclosed
US-20090156800-A1 PROCESS FOR MAKING MACROCYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. 2009-06-18 US disclosed
US-20090156822-A1 Hepatitis C Inhibitor Dipeptide Analogs BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-18 US disclosed
US-20090156822-A1 Hepatitis C Inhibitor Dipeptide Analogs BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-18 US disclosed
US-7511157-B2 racemic mixtures, stereoisomers or optical isomers, useful as protease inhibitors; viricides BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-03-31 US disclosed
US-7511157-B2 racemic mixtures, stereoisomers or optical isomers, useful as protease inhibitors; viricides BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-03-31 US disclosed
EP-1497373-B1 THERMOSET COMPOSITION, METHOD, AND ARTICLE GEN ELECTRIC (US) 2007-02-07 EP disclosed
US-4306047-A Propylene polymerization SHELL OIL COMPANY (US) 1981-12-15 US disclosed
US-4269732-A Olefin polymerization catalysts SHELL OIL COMPANY (US) 1981-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156822-A1 Hepatitis C Inhibitor Dipeptide Analogs DPP3, CTSC, ANPEP CYP1A2 1856/4885RIPK1 1681/4885
US-20170334815-A1 CATALYST AND METHOD FOR HYDROGENATION OF 1,3-CYCLOBUTANEDIKETONE COMPOUND CXXC5, ZRANB2, GZMB CYP1A2 1940/4885RIPK1 3889/4885
US-20230348388-A1 Highly Purified Batches Of Pharmaceutical Grade Migalastat And Methods Of Producing The Same GANAB, GALK1, GANC CYP1A2 2076/4885RIPK1 2187/4885
US-20180057505-A1 BICYCLIC HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF THE PAR-2 SIGNALING PATHWAY F2RL1, PARP12, TFPI2 CYP1A2 594/4885RIPK1 351/4885
US-20200407371-A1 SMALL MOLECULES FOR INDUCING SELECTIVE PROTEIN DEGRADATION AND USES THEREOF BAZ2A, BRD3, BRPF3 CYP1A2 4582/4885RIPK1 211/4885
US-20090191153-A1 OXIMYL MACROCYCLIC DERIVATIVES CYP3A4, CYP4A22, HCCS CYP1A2 104/4885RIPK1 1230/4885
US-11685718-B2 Highly purified batches of pharmaceutical grade 1-deoxygalactonojirimycin compounds GALK1, GANAB, MGAM CYP1A2 1699/4885RIPK1 2378/4885
US-11802132-B2 Small molecules for inducing selective protein degradation and uses thereof BAZ2A, BRD3, BRPF3 CYP1A2 4582/4885RIPK1 211/4885
US-20230330254-A1 ANTI-GLP1R ANTIBODY-TETHERED DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF GLP1R, GIPR, GCGR CYP1A2 4174/4885RIPK1 2507/4885
US-20090156800-A1 PROCESS FOR MAKING MACROCYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS PREP, HCCS, PEPD CYP1A2 278/4885RIPK1 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.