Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463336 | 0.87 | RIPK1 (0.32) | RIPK1CA2TDP1 | |
| SCHEMBL28536189 | 0.82 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL29242539 | 0.77 | CA1 (0.33) | CA2 | |
| SCHEMBL10044964 | 0.77 | CYP1A2 (0.38) | RIPK1CYP1A2 | |
| SCHEMBL17433678 | 0.76 | CA2 (0.37) | RIPK1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL21470066 | 0.74 | ALDH1A1 (0.35) | CA2MAPK1ALDH1A1 | |
| SCHEMBL2467543 | 0.74 | TP53 (0.40) | TP53ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL19056892 | 0.74 | TP53 (0.40) | TP53ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL11457365 | 0.73 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL12060203 | 0.73 | TSHR (0.31) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527870-B2 | Organosiloxane compositions | DOW CORNING CORPORATION (US) | 2009-05-05 | — | — | US | disclosed |
| EP-1620491-B1 | MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS | DOW CORNING (US) | 2007-04-25 | — | — | EP | disclosed |
| US-20060194067-A1 | Organosiloxane compositions | DOW SILICONES CORPORATION | 2006-08-31 | — | — | US | disclosed |
| US-7022800-B2 | Organosiloxane compositions | DOW CORNING S.A. (BE) | 2006-04-04 | — | — | US | disclosed |
| EP-1620491-A1 | MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004094503-A1 | MOISTURE CURABLE ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040214965-A1 | Organosiloxane compositions | DOW CORNING S.A. (BE) | 2004-10-28 | — | — | US | disclosed |
| EP-1254192-B1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING SA (BE) | 2004-08-04 | — | — | EP | disclosed |
| EP-1254192-A2 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING S.A. (BE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001049789-A2 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING S.A. (BE) | 2001-07-12 | — | — | WO | disclosed |