Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21219198 | 0.92 | ALDH1A1 (0.41) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL28313554 | 0.90 | MAPT (0.41) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL28541140 | 0.90 | ALDH1A1 (0.43) | L3MBTL1MAPTTDP1CYP2C9SMN1; SMN2 | |
| SCHEMBL28654549 | 0.90 | ALDH1A1 (0.39) | L3MBTL1MAPTCYP2C9SMN1; SMN2CYP1A2 | |
| SCHEMBL28537870 | 0.88 | ALDH1A1 (0.40) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL28559501 | 0.87 | ALDH1A1 (0.41) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL21815478 | 0.84 | MEN1 (0.47) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL4420431 | 0.83 | L3MBTL1 (0.42) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL28380826 | 0.83 | TSHR (0.39) | L3MBTL1MAPTRAB9AATMTSHR | |
| SCHEMBL28354485 | 0.83 | TSHR (0.39) | L3MBTL1MAPTRAB9AATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112638477-A | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110637022-A | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2019-12-31 | — | — | CN | disclosed |