Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654549 | 0.99 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL28559501 | 0.96 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL28313554 | 0.92 | MAPT (0.41) | ALDH1A1MAPTCYP1A2CYP2C9GAA | |
| SCHEMBL28541140 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL28536772 | 0.88 | L3MBTL1 (0.38) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL21219198 | 0.88 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL3889830 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL22973084 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL21751770 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL28351010 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112638477-A | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110637022-A | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2019-12-31 | — | — | CN | disclosed |