Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541522 | 0.90 | CYP1A2 (0.48) | CYP2D6CYP2C19CYP1A2POLBPIN1 | |
| SCHEMBL28911447 | 0.88 | SMN1; SMN2 (0.45) | CYP2D6CYP2C19CYP1A2LMNANPSR1 | |
| SCHEMBL28544709 | 0.87 | LMNA (0.47) | CYP2C19CYP1A2LMNASMN1; SMN2RAB9A | |
| SCHEMBL8888696 | 0.82 | TDP1 (0.41) | CYP2D6CYP2C19CYP1A2LMNASMN1; SMN2 | |
| SCHEMBL7861200 | 0.81 | PIN1 (0.50) | CYP2D6CYP2C19CYP1A2LMNAPOLB | |
| SCHEMBL28421404 | 0.81 | PIN1 (0.50) | CYP2C19CYP1A2LMNAPOLBNPSR1 | |
| SCHEMBL8462212 | 0.80 | TDP1 (0.50) | CYP2D6CYP2C19CYP1A2LMNAHIF1A | |
| SCHEMBL632178 | 0.79 | CES1 (0.51) | CYP2D6CYP2C19CYP1A2LMNAHIF1A | |
| SCHEMBL6924315 | 0.77 | MEN1 (0.48) | CYP2D6CYP2C19CYP1A2POLBNPSR1 | |
| SCHEMBL27485518 | 0.77 | PIN1 (0.46) | CYP2C19POLBNPSR1PIN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553705-B | Catalyst component for olefin polymerization and preparation method thereof | 中国石油化工股份有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-109553712-B | Catalyst component for olefin polymerization and catalyst thereof | 中国石油化工股份有限公司 | 2021-03-16 | — | — | CN | claimed |