Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | FBP1 | P09467 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142930 | 0.94 | THRB (0.44) | THRBFBP1ATMTDP1MAPT | |
| SCHEMBL11152796 | 0.89 | NPSR1 (0.46) | THRBFBP1ATMTDP1MAPT | |
| SCHEMBL30875142 | 0.86 | THRB (0.44) | THRBFBP1ATMTDP1MAPT | |
| SCHEMBL14035563 | 0.86 | THRB (0.44) | THRBFBP1ATMTDP1MAPT | |
| SCHEMBL3714543 | 0.86 | ATM (0.50) | ATMTDP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3714548 | 0.86 | ATM (0.50) | ATMTDP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL112748 | 0.84 | THRB (0.45) | THRBFBP1ATMTDP1MAPT | |
| SCHEMBL11147475 | 0.84 | SMN1; SMN2 (0.43) | THRBATMTDP1MAPTALDH1A1 | |
| SCHEMBL2300748 | 0.84 | THRB (0.44) | THRBFBP1ATMTDP1MAPT | |
| SCHEMBL28566529 | 0.84 | ATM (0.43) | THRBFBP1ATMTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225657-B | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-112225657-B | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-112225657-A | Preparation method of flurbiprofen | 北京泰德制药股份有限公司 | 2021-01-15 | — | — | CN | disclosed |