Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142930 | 0.87 | THRB (0.44) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL14035563 | 0.87 | THRB (0.44) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL30875142 | 0.87 | THRB (0.44) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL2300748 | 0.87 | THRB (0.44) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL112748 | 0.85 | THRB (0.45) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL28537382 | 0.84 | THRB (0.42) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL11152796 | 0.83 | NPSR1 (0.46) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL3660772 | 0.82 | MAPT (0.38) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL142931 | 0.82 | ALDH1A1 (0.56) | ATMTDP1MAPTTHRBFBP1 | |
| SCHEMBL5643422 | 0.81 | POLB (0.40) | ATMTDP1MAPTTHRBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283539-A | Preparation method of 2,4, 5-trifluoro phenylacetic acid | 安庆朗坤药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-112851493-B | Preparation method of 2,4, 5-trifluoro phenylacetic acid | 台州臻挚生物科技有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-112851493-A | Preparation method of 2,4, 5-trifluorophenylacetic acid | 杭州臻挚生物科技有限公司 | 2021-05-28 | — | — | CN | disclosed |