Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713222 | 0.80 | TSHR (0.57) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL158497 | 0.79 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11072823 | 0.79 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL10985089 | 0.77 | ALDH1A1 (0.72) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1684895 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27776511 | 0.77 | TSHR (0.53) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL12994041 | 0.77 | TSHR (0.53) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL13437771 | 0.76 | TSHR (0.52) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL14434126 | 0.74 | ALDH1A1 (0.52) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL2223429 | 0.73 | TSHR (0.63) | TSHRALDH1A1POLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108017573-B | Process for preparing 4-methylenepiperidine or acid addition salt thereof | 山东特珐曼药业有限公司 | 2021-03-26 | — | — | CN | disclosed |