Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27776511 | 0.98 | TSHR (0.53) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL4516367 | 0.93 | TSHR (0.49) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL568818 | 0.88 | TSHR (0.47) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL11072823 | 0.88 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1713222 | 0.85 | TSHR (0.57) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Ethylene SCHEMBL8377868 | 0.83 | POLB (0.45) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1444915 | 0.83 | SMN1; SMN2 (0.61) | TSHRALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL8490392 | 0.83 | CHRM1 (0.62) | TSHRALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL10985089 | 0.82 | ALDH1A1 (0.72) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1684895 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176986-A1 | Process for the Preparation of Pyridine Heterocycle Cgrp Antagonist Intermediate | MERCK SHARP & DOHME CORP. | 2009-07-09 | — | — | US | claimed |
| EP-2007763-A2 | PROCESS FOR THE PREPARATION OF PYRIDINE HETEROCYCLE CGRP ANTAGONIST INTERMEDIATE | Merck & Co., Inc. (US) | 2008-12-31 | — | — | EP | claimed |
| WO-2007120590-A2 | PROCESS FOR THE PREPARATION OF PYRIDINE HETEROCYCLE CGRP ANTAGONIST INTERMEDIATE | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | claimed |
| WO-2005013913-A2 | PEROXYGEN CONTAINING PARTICLE IN AN ALCOHOL CONTAINING GEL | MATERIALS TECHNOLOGY LABORATORIES, INC. (US) | 2005-02-17 | — | — | WO | claimed |
| EP-0721452-B1 | PROCESS FOR THE PREPARATION OF SUFENTANIL DERIVATIVES BY CARBENE ADDITION/AMINOLYSIS OF 4-PIPERIDONE | MALLINCKRODT INC (US) | 2001-06-20 | — | — | EP | claimed |
| US-6084100-A | REACTING 8-CHLORO-5,6-DIHYDROBENZO(5,6)CYCLOHEPTA(1,2-B)-PYRIDIN-11-ONE AND ETHYL 4-OXOPIPERIDINE-1-CARBOXYLATE IN AN ORGANIC SOLVENT IN THE PRESENCE OF A TERTIARY AMINE WITH A LOW-VALENT TITANIUM COMPOUND; CROSS REDUCTIVE COUPLING | MEDICHEM, S.A. (ES) | 2000-07-04 | — | — | US | claimed |
| WO-1999023196-A1 | LIQUID AQUEOUS BLEACHING COMPOSITIONS PACKAGED IN A UV RESISTANT CONTAINER | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1999023197-A1 | PROCESSES OF SOAKING FABRICS WITH A LIQUID AQUEOUS PERSULFATE SALT-CONTAINING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1999023294-A1 | PROCESSES OF BLEACHING FABRICS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| WO-1999023195-A1 | MULTI-PURPOSE LIQUID AQUEOUS BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1999-05-14 | — | — | WO | claimed |
| EP-0721452-A1 | PROCESS FOR THE PREPARATION OF SUFENTANIL DERIVATIVES BY CARBENE ADDITION/AMINOLYSIS OF 4-PIPERIDONE | Mallinckrodt Chemical, Inc. (US) | 1996-07-17 | — | — | EP | claimed |
| US-5489689-A | CONDENSING A PIPERIDONE WITH A PRIMARY AMINE TO FORM A 4-AMINO-4-CARBOXYAMINOPIPERIDINE; HYDROLYSIS; CONDENSATION WITH A MESYLATE CONTAINING A PHENYL, THIENYL OR 4-ETHYL-4,5-DIHYDRO-5-OXO-1H-TETRAZPINE | MALLINCKRODT CHEMICAL, INC. (US) | 1996-02-06 | — | — | US | claimed |
| WO-1995009152-A1 | PROCESS FOR THE PREPARATION OF SUFENTANIL DERIVATIVES BY CARBENE ADDITION/AMINOLYSIS OF 4-PIPERIDONE | MALLINCKRODT CHEMICAL, INC. (US) | 1995-04-06 | — | — | WO | claimed |
| JP-9100281-A | — | — | None | — | — | JP | disclosed |
| US-12590091-B2 | 1H-pyrrolo[3,2-C]pyridine and 1H-pyrrolo[2,3-C]pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-03-31 | — | — | US | disclosed |
| US-12583862-B2 | Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway | NURIX THERAPEUTICS, INC. (US) | 2026-03-24 | — | — | US | disclosed |
| US-4014890-A | REACTING A PHENYLHYDRAZINE SALT AND A KETONE IN A WEAK BASE | PFIZER INC. (US) | 1977-03-29 | — | — | US | disclosed |
| US-4005208-A | GASTRIC JUICE, ANTISECRETORY | SMITHKLINE CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001263-A | TRANQUILIZERS | PFIZER INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3954754-A | ANTIHYPERTENSIVES | SANDOZ LTD. (CH) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176986-A1 | Process for the Preparation of Pyridine Heterocycle Cgrp Antagonist Intermediate | CCKBR, CALCRL, CALCR | TSHR 645/4885ALDH1A1 1104/4885POLB 2517/4885 |
| US-12590091-B2 | 1H-pyrrolo[3,2-C]pyridine and 1H-pyrrolo[2,3-C]pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis | TLR9, TLR1, TLR3 | TSHR 789/4885ALDH1A1 3124/4885POLB 443/4885 |
| US-12583862-B2 | Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway | BTK, PSMB2, PSME3 | TSHR 3211/4885ALDH1A1 4714/4885POLB 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.