Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295195 | 0.86 | CDC7 (0.53) | CDC7CDK2PARP1CYP2C19SLC22A12 | |
| SCHEMBL2295522 | 0.85 | CDC7 (0.49) | CDC7CDK2BRAFPARP1CYP2C19 | |
| SCHEMBL30828406 | 0.84 | CDC7 (0.54) | CDC7CDK2BRAFPARP1CYP2C19 | |
| SCHEMBL1150333 | 0.84 | CDC7 (0.54) | CDC7CDK2BRAFPARP1CYP2C19 | |
| SCHEMBL27839782 | 0.83 | BIRC5 (0.54) | CDC7CDK2PARP1CYP2C19SLC22A12 | |
| SCHEMBL20603929 | 0.83 | CDC7 (0.58) | CDC7CDK2PARP1CYP2C19HTT | |
| SCHEMBL7892111 | 0.83 | CDC7 (0.50) | CDC7CDK2BRAFPARP1CYP2C19 | |
| SCHEMBL28537449 | 0.83 | L3MBTL1 (0.54) | CDC7CDK2BRAFPARP1CYP2C19 | |
| SCHEMBL2295440 | 0.82 | CDC7 (0.56) | CDC7CDK2PARP1CYP2C19SLC22A12 | |
| Hydrochloric Acid SCHEMBL30335602 | 0.81 | CDC7 (0.51) | CDC7CDK2PARP1CYP2C19SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480111-A | Synthesis method of 7-azaindole substituted aryl acetate compound | 江苏理工学院 | 2021-03-12 | — | — | CN | disclosed |