Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395483 | 0.84 | CYP19A1 (0.42) | BRAFCDC7CDK2RAB9AMAPT | |
| SCHEMBL4809563 | 0.83 | NOS3 (0.39) | BRAFCDC7CDK2CLK4AURKA | |
| SCHEMBL4809566 | 0.83 | NOS3 (0.39) | BRAFCDC7CDK2CLK4AURKA | |
| SCHEMBL14194642 | 0.83 | NOS3 (0.39) | BRAFCDC7CDK2CLK4AURKA | |
| SCHEMBL28537449 | 0.82 | L3MBTL1 (0.54) | BRAFCDC7CDK2PTK2MAPT | |
| SCHEMBL2295195 | 0.82 | CDC7 (0.53) | CDC7CDK2RAB9ANPC1SLC22A12 | |
| SCHEMBL28553993 | 0.81 | MAPT (0.44) | BRAFCDC7CDK2METRAB9A | |
| SCHEMBL5314321 | 0.81 | SLC22A12 (0.47) | CDC7CDK2PDGFRBPDGFRAPTK2 | |
| SCHEMBL30828406 | 0.80 | CDC7 (0.54) | BRAFCDC7CDK2ALDH1A1SLC22A12 | |
| SCHEMBL1150333 | 0.80 | CDC7 (0.54) | BRAFCDC7CDK2ALDH1A1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480111-A | Synthesis method of 7-azaindole substituted aryl acetate compound | 江苏理工学院 | 2021-03-12 | — | — | CN | disclosed |