Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.76 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.76 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 11/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA5A | P35218 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12246778 | 0.87 | APP (0.81) | TTRAKR1B10AKR1B1DPP4APP | |
| SCHEMBL29689052 | 0.87 | APP (0.81) | TTRAKR1B10AKR1B1DPP4APP | |
| SCHEMBL30683157 | 0.86 | TTR (0.76) | TTRAKR1B10AKR1B1DPP4APP | |
| SCHEMBL26932236 | 0.86 | TTR (0.76) | TTRAKR1B10AKR1B1DPP4APP | |
| Benzyl Caffeate SCHEMBL1877243 | 0.86 | AKR1B10 (1.00) | TTRAKR1B10AKR1B1DPP4APP | |
| Benzyl Caffeate SCHEMBL1659796 | 0.86 | AKR1B10 (1.00) | TTRAKR1B10AKR1B1DPP4APP | |
| SCHEMBL29087463 | 0.86 | CA12 (0.73) | TTRAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL28003361 | 0.86 | TTR (0.70) | TTRAKR1B10AKR1B1DPP4APP | |
| Ethyl Caffeate SCHEMBL22196845 | 0.83 | TTR (1.00) | TTRAKR1B10AKR1B1DPP4APP | |
| Ethyl Caffeate SCHEMBL31059266 | 0.83 | TTR (1.00) | TTRAKR1B10AKR1B1DPP4APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112691099-B | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2022-09-30 | — | — | CN | claimed |
| CN-112691099-A | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2021-04-23 | — | — | CN | claimed |
| CN-112624927-B | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-112691099-B | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-112691099-A | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-112624927-A | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2021-04-09 | — | — | CN | disclosed |