Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 4/20 | 1.00 |
| ▸ | TTR | P02766 | 4/20 | 1.00 |
| ▸ | APP | P05067 | 9/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | GMNN | O75496 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 1/20 | 0.76 |
| ▸ | ESR1 | P03372 | 1/20 | 0.76 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.76 |
| ▸ | LCK | P06239 | 1/20 | 0.76 |
| ▸ | FYN | P06241 | 1/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Caffeate SCHEMBL1877243 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL25647016 | 0.89 | TTR (0.81) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL19163944 | 0.88 | AKR1B10 (0.78) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL13552179 | 0.86 | LMNA (0.93) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL26932236 | 0.86 | TTR (0.76) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL30683157 | 0.86 | TTR (0.76) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| Caffeic Acid Phenethyl Ester SCHEMBL28294426 | 0.86 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| Caffeic Acid Phenethyl Ester SCHEMBL30070826 | 0.86 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL28537490 | 0.86 | TTR (0.76) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| Caffeic Acid Phenethyl Ester SCHEMBL93649 | 0.86 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119523819-A | Light-responsive antioxidant preparation, and preparation method and application thereof | 上海百雀羚生物科技有限公司 | 2025-02-28 | — | — | CN | claimed |
| WO-2024136261-A1 | ANTI-INFLAMMATORY OR ANTIOXIDANT COMPOSITION COMPRISING BENZYL CAFFEATE AS ACTIVE INGREDIENT | 동아대학교 산학협력단 | 2024-06-27 | — | — | WO | claimed |
| CN-105307665-B | Therapeutic compositions and uses thereof | 蜜纽康新西兰有限公司 | 2021-09-28 | — | — | CN | claimed |
| EP-2983681-B1 | THERAPEUTIC COMPOSITIONS AND USES THEREOF | MANUKA HEALTH NEW ZEALAND LTD (NZ) | 2020-07-15 | — | — | EP | claimed |
| EP-3169321-B1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | MANUKA HEALTH NEW ZEALAND LTD (NZ) | 2020-07-15 | — | — | EP | claimed |
| US-20170209499-A1 | Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2017-07-27 | — | — | US | claimed |
| EP-3169321-A1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | Manuka Health New Zealand Limited (NZ) | 2017-05-24 | — | — | EP | claimed |
| CN-104592188-B | A kind of isolated and purified pinobanksin and method of caffeinic derivant from China's Water extracts of propolis | 聊城大学 | 2016-08-24 | — | — | CN | claimed |
| US-20160051594-A1 | Therapeutic Compositions and Uses Thereof | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2016-02-25 | — | — | US | claimed |
| EP-2983681-A1 | THERAPEUTIC COMPOSITIONS AND USES THEREOF | Manuka Health New Zealand Limited (NZ) | 2016-02-17 | — | — | EP | claimed |
| WO-2016010440-A1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2016-01-21 | — | — | WO | claimed |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | UNIVERSITÉ CLERMONT AUVERGNE (FR) | 2015-10-01 | — | — | US | claimed |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE CLERMONT FERRAND (FR) | 2015-02-05 | — | — | US | claimed |
| WO-2014163513-A1 | THERAPEUTIC COMPOSITIONS AND USES THEREOF | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2014-10-09 | — | — | WO | claimed |
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | MOLECULIN, L.L.C. | 2008-07-10 | — | — | US | claimed |
| WO-2008083389-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | MOLECULIN, L.L.C. (US) | 2008-07-10 | — | — | WO | claimed |
| WO-2001078783-A2 | COMPOSITIONS COMPRISING NATURAL AGENTS FOR TREATMENT OF CANCER | HAUSER, INC. (US) | 2001-10-25 | — | — | WO | claimed |
| CN-117402197-B | Vitex negundo extract and preparation method thereof and identification method of Vitex negundo honey | 江苏蜂奥生物科技有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-1666440-A1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2001078783-A2 | COMPOSITIONS COMPRISING NATURAL AGENTS FOR TREATMENT OF CANCER | HAUSER, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | CYP24A1, VDR, CYP2R1 | AKR1B10 2192/4885AKR1B1 1890/4885TTR 2718/4885 |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | AKR1B10 1601/4885AKR1B1 1390/4885TTR 1663/4885 |
| US-20170209499-A1 | Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health | CUTA, DSC1, DACH1 | AKR1B10 2559/4885AKR1B1 3052/4885TTR 2239/4885 |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | AKR1B10 1601/4885AKR1B1 1390/4885TTR 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.