Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 4/20 | 1.00 |
| ▸ | TTR | P02766 | 4/20 | 1.00 |
| ▸ | APP | P05067 | 9/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | GMNN | O75496 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 1/20 | 0.76 |
| ▸ | ESR1 | P03372 | 1/20 | 0.76 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.76 |
| ▸ | LCK | P06239 | 1/20 | 0.76 |
| ▸ | FYN | P06241 | 1/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Caffeate SCHEMBL1659796 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL25647016 | 0.89 | TTR (0.81) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL19163944 | 0.88 | AKR1B10 (0.78) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL13552179 | 0.86 | LMNA (0.93) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL26932236 | 0.86 | TTR (0.76) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL30683157 | 0.86 | TTR (0.76) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| Caffeic Acid Phenethyl Ester SCHEMBL28294426 | 0.86 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| Caffeic Acid Phenethyl Ester SCHEMBL30070826 | 0.86 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| SCHEMBL28537490 | 0.86 | TTR (0.76) | AKR1B10AKR1B1TTRAPPCYP3A4 | |
| Caffeic Acid Phenethyl Ester SCHEMBL93649 | 0.86 | AKR1B10 (1.00) | AKR1B10AKR1B1TTRAPPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402197-B | Vitex negundo extract and preparation method thereof and identification method of Vitex negundo honey | 江苏蜂奥生物科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-117402197-A | Vitex negundo extract and preparation method thereof and identification method of Vitex negundo honey | 江苏蜂奥生物科技有限公司 | 2024-01-16 | — | — | CN | claimed |
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |
| CN-105307665-B | Therapeutic compositions and uses thereof | 蜜纽康新西兰有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-104592188-B | A kind of isolated and purified pinobanksin and method of caffeinic derivant from China's Water extracts of propolis | 聊城大学 | 2016-08-24 | — | — | CN | claimed |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | UNIVERSITÉ CLERMONT AUVERGNE (FR) | 2015-10-01 | — | — | US | claimed |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE CLERMONT FERRAND (FR) | 2015-02-05 | — | — | US | claimed |
| US-12605352-B2 | Compositions and methods for inhibiting blood cancer cell growth | THE UNIVERSITY OF NEW BRUNSWICK (CA) | 2026-04-21 | — | — | US | disclosed |
| US-20240425441-A9 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ICOSA PHARMA INC. (CA) | 2024-12-26 | — | — | US | disclosed |
| WO-2024136261-A1 | ANTI-INFLAMMATORY OR ANTIOXIDANT COMPOSITION COMPRISING BENZYL CAFFEATE AS ACTIVE INGREDIENT | 동아대학교 산학협력단 | 2024-06-27 | — | — | WO | disclosed |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-12-07 | — | — | US | disclosed |
| EP-4276089-A2 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | Universite De Moncton (CA) | 2023-11-15 | — | — | EP | disclosed |
| EP-4276089-A2 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | Universite De Moncton (CA) | 2023-11-15 | — | — | EP | disclosed |
| US-20100152143-A1 | Methods of Treating Skin Disorders with Caffeic Acid Analogs | MOLECULIN, LLC (US) | 2010-06-17 | — | — | US | disclosed |
| US-7700642-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-11 | — | — | US | disclosed |
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | MOLECULIN, L.L.C. | 2008-07-10 | — | — | US | disclosed |
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | MOLECULIN, L.L.C. | 2008-07-10 | — | — | US | disclosed |
| EP-1666440-A1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152143-A1 | Methods of Treating Skin Disorders with Caffeic Acid Analogs | CUTA, TYR, PPARA | AKR1B10 1463/4885AKR1B1 1210/4885TTR 2325/4885 |
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | CYP24A1, VDR, CYP2R1 | AKR1B10 2192/4885AKR1B1 1890/4885TTR 2718/4885 |
| US-20240425441-A9 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ALOX12, ALOX15B, ALOX5 | AKR1B10 392/4885AKR1B1 182/4885TTR 3270/4885 |
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | AHR, AR, ARSA | AKR1B10 74/4885AKR1B1 44/4885TTR 3961/4885 |
| US-20230391711-A1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | ALOX12, ALOX15B, ALOX5 | AKR1B10 392/4885AKR1B1 182/4885TTR 3270/4885 |
| US-20150038466-A1 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | AKR1B10 1601/4885AKR1B1 1390/4885TTR 1663/4885 |
| US-20150274633-A2 | PAIN RELIEF COMPOUNDS | OPRL1, OPRK1, TRPV1 | AKR1B10 1601/4885AKR1B1 1390/4885TTR 1663/4885 |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | AHR, AR, ARSA | AKR1B10 74/4885AKR1B1 44/4885TTR 3961/4885 |
| US-12605352-B2 | Compositions and methods for inhibiting blood cancer cell growth | MCL1, HRH2, SLC25A11 | AKR1B10 2410/4885AKR1B1 2335/4885TTR 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.