Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 5/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422650 | 0.80 | MEN1 (0.36) | GPR119SMN1; SMN2 | |
| SCHEMBL31038329 | 0.74 | GPR119 (0.46) | GPR119CYP4F2CYP4A11ACACBRORC | |
| SCHEMBL25243983 | 0.74 | GPR119 (0.46) | GPR119CYP4F2CYP4A11ACACBRORC | |
| SCHEMBL25365054 | 0.74 | GPR119 (0.46) | GPR119CYP4F2CYP4A11ACACBRORC | |
| SCHEMBL31554865 | 0.74 | GPR119 (0.46) | GPR119CYP4F2CYP4A11ACACBRORC | |
| SCHEMBL28430025 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL29227973 | 0.69 | GPR119 (0.39) | GPR119CYP4F2CYP4A11ACACBRORC | |
| SCHEMBL28892258 | 0.68 | GRM4 (0.38) | GPR119MAPTSMN1; SMN2 | |
| SCHEMBL15772111 | 0.68 | GPR119 (0.54) | GPR119CYP4F2CYP4A11RORCMAPT | |
| SCHEMBL15772581 | 0.68 | GPR119 (0.52) | GPR119CYP4F2CYP4A11RORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |