Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537682 | 0.80 | GPR119 (0.45) | GPR119SMN1; SMN2 | |
| SCHEMBL28430025 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL28427037 | 0.69 | AR (0.30) | — | |
| SCHEMBL20007513 | 0.69 | TRPV4 (0.39) | MEN1POLBKMT2ALMNASMYD3 | |
| SCHEMBL28892258 | 0.68 | GRM4 (0.38) | MEN1KMT2ANFE2L2LMNASMYD3 | |
| SCHEMBL219187 | 0.67 | PARL (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2645976 | 0.67 | NFE2L2 (0.41) | MEN1POLBKMT2ANFE2L2GPR119 | |
| SCHEMBL423199 | 0.65 | GPR119 (0.39) | POLBNFE2L2LMNASMYD3GPR119 | |
| SCHEMBL1465207 | 0.65 | NFE2L2 (0.42) | MEN1POLBKMT2ANFE2L2ALDH1A1 | |
| SCHEMBL30727325 | 0.64 | NFE2L2 (0.39) | MEN1POLBKMT2ANFE2L2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333626-B | Phenyl pyrrolidine compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-111333626-A | Phenyl pyrrolidine compounds and uses thereof | 湖北生物医药产业技术研究院有限公司 | 2020-06-26 | — | — | CN | disclosed |