Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807159 | 0.81 | ALDH1A1 (0.46) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL4934011 | 0.80 | SMN1; SMN2 (0.40) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL776566 | 0.79 | CES2 (0.55) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL27553353 | 0.79 | CES2 (0.55) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL11862575 | 0.79 | CES2 (0.55) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL248821 | 0.79 | CES2 (0.55) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL6939791 | 0.79 | CES2 (0.55) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL777438 | 0.79 | CES2 (0.41) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL18126504 | 0.79 | NAAA (0.44) | CES2CES1ALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL776049 | 0.78 | ALDH1A1 (0.43) | CES2CES1ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-A | Prophylactic or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2021-03-09 | — | — | CN | disclosed |