Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.71 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21791658 | 0.92 | LOXL2 (0.71) | PDPK1LOXL2ADRB2CYP2A6CYP17A1 | |
| SCHEMBL5147639 | 0.84 | PDPK1 (0.91) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| 2-Phenylthiazole SCHEMBL70646 | 0.84 | PDPK1 (1.00) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| 2-Phenylthiazole SCHEMBL28319382 | 0.82 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| 2-Phenylthiazole SCHEMBL10519953 | 0.82 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| 2-Phenylthiazole SCHEMBL4939218 | 0.82 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| 2-Phenylthiazole SCHEMBL10667585 | 0.82 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| 2-Phenylthiazole SCHEMBL27882225 | 0.82 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| SCHEMBL722198 | 0.82 | PDPK1 (0.77) | PDPK1LOXL2ADRB2CYP2A6PTGDR2 | |
| SCHEMBL5533749 | 0.81 | LOXL2 (0.62) | PDPK1LOXL2ADRB2CYP2A6LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204507-B | Process for producing 2-aryl-4-alkylthiazole compound | 浙江大学 | 2021-03-02 | — | — | CN | disclosed |