SCHEMBL28538482

SCHEMBL28538482

S=C1NC(c2ccccc2)CO1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
PKM P14618 1/20 0.38
ALOX12 P18054 1/20 0.38
RAB9A P51151 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
AR P10275 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PRCP P42785 1/20 0.36
NPC1 O15118 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
HDAC3 O15379 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
NCOR2 Q9Y618 2/20 0.34
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28538480 1.00 TSHR (0.40) TSHRALDH1A1HPGDKDM4EPKM
SCHEMBL2933208 0.81 ALDH1A1 (0.36) TSHRALDH1A1HPGDKDM4EPKM
SCHEMBL16106147 0.76 SMN1; SMN2 (0.42) TSHRALDH1A1HPGDKDM4EAR
SCHEMBL4563 0.76 SMN1; SMN2 (0.42) TSHRALDH1A1HPGDKDM4EAR
SCHEMBL445133 0.76 SMN1; SMN2 (0.42) TSHRALDH1A1HPGDKDM4EAR
SCHEMBL4562 0.76 SMN1; SMN2 (0.42) TSHRALDH1A1HPGDKDM4EAR
SCHEMBL4532571 0.74 AR (0.41) TSHRARHDAC3HDAC1HDAC2
SCHEMBL2909384 0.74 AR (0.41) TSHRALDH1A1ARMEN1KMT2A
SCHEMBL6436184 0.73 MEN1 (0.49) TSHRALDH1A1KDM4ETDP1AR
SCHEMBL14654002 0.73 TSHR (0.38) TSHRALDH1A1HPGDKDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500361-B Preparation method of (S) -4-phenyl-2-oxazolidinone 甘肃瀚聚药业有限公司 2023-05-12 CN claimed
CN-112500361-A Preparation method of (S) -4-phenyl-2-oxazolidinone 甘肃瀚聚药业有限公司 2021-03-16 CN claimed
CN-112500361-A Preparation method of (S) -4-phenyl-2-oxazolidinone 甘肃瀚聚药业有限公司 2021-03-16 CN disclosed