Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1454571 | 0.84 | MTNR1A (0.47) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL27526890 | 0.83 | MTNR1A (0.44) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL51170 | 0.80 | MTNR1A (0.41) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL11516903 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL4633428 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL8733440 | 0.78 | MTNR1A (0.50) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL9870637 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL9870647 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 | |
| SCHEMBL21985789 | 0.74 | RCE1 (0.46) | HTR2A | |
| SCHEMBL1455296 | 0.73 | MTNR1A (0.45) | MTNR1AMTNR1BLMNACHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948671-B1 | PREPARATION OF CATALYSTS | BOEHRINGER INGELHEIM INT (DE) | 2010-09-29 | — | — | EP | disclosed |