Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59001 | 0.85 | APP (0.73) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Phosphoric Acid SCHEMBL10591537 | 0.82 | APP (0.57) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Ethyne SCHEMBL9049731 | 0.80 | APP (0.67) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Phosphonic Acid SCHEMBL28034212 | 0.80 | CES2 (0.50) | ALDH1A1NPC1RAB9A | |
| SCHEMBL11711659 | 0.78 | RAB9A (0.68) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL9292264 | 0.78 | MAPT (0.79) | APPALDH1A1TSHRALOX15KMT2A | |
| Cyclopropane SCHEMBL28538522 | 0.78 | APP (0.64) | APPALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL7052585 | 0.78 | APP (0.64) | APPALDH1A1TSHRALOX15HSD17B10 | |
| Phosphonic Acid SCHEMBL11719755 | 0.76 | RAB9A (0.54) | ALDH1A1TSHRALOX15HSD17B10KMT2A | |
| SCHEMBL4265855 | 0.74 | APP (0.59) | APPALDH1A1TSHRALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861712-A | Analysis element for determination of a coagulation parameter | BOEHRINGER MANNEHEIM GMBH (DE) | 1989-08-29 | — | — | US | disclosed |