SCHEMBL28538634

SCHEMBL28538634

COC(=O)c1ccc(C(=O)OC)c(-c2ccc(/N=N/c3ccccc3)cc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.66
RAB9A P51151 3/20 0.66
CASP3 P42574 1/20 0.66
SENP8 Q96LD8 1/20 0.66
SENP7 Q9BQF6 1/20 0.66
SENP6 Q9GZR1 1/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
PTGS2 P35354 1/20 0.51
ALDH1A1 P00352 4/20 0.50
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 2/20 0.50
EGFR P00533 1/20 0.50
SLC6A3 Q01959 4/20 0.47
SLC6A4 P31645 3/20 0.47
KDM4E B2RXH2 2/20 0.47
GLA P06280 2/20 0.47
GAA P10253 2/20 0.47
ATM Q13315 2/20 0.47
CASP1 P29466 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818748 0.87 PTGS2 (0.59) MAPTPTGS2ALDH1A1HPGDSMN1; SMN2
SCHEMBL8678283 0.84 KDM4E (0.59) MAPTPTGS2ALDH1A1HPGDSMN1; SMN2
SCHEMBL28968875 0.82 MAPT (0.67) MAPTRAB9ACASP3SENP8SENP7
SCHEMBL1405345 0.81 RAB9A (1.00) MAPTRAB9ACASP3SENP8SENP7
SCHEMBL1405346 0.81 RAB9A (1.00) MAPTRAB9ACASP3SENP8SENP7
SCHEMBL30571934 0.80 TDP1 (0.59) MAPTRAB9AL3MBTL1PTGS2ALDH1A1
SCHEMBL9423312 0.80 TDP1 (0.59) MAPTRAB9AL3MBTL1PTGS2ALDH1A1
Azobenzene SCHEMBL28526739 0.79 RAB9A (0.96) MAPTRAB9ACASP3SENP8SENP7
SCHEMBL15771108 0.79 TRPA1 (0.61) MAPTRAB9ACASP3SENP8SENP7
SCHEMBL26573338 0.79 KDM4E (0.65) MAPTPTGS2ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480381-B Photochromic azobenzene polyester, preparation method thereof and photochromic polyester fiber 武汉纺织大学 2022-08-30 CN disclosed
CN-112480381-A Photochromic azobenzene polyester, preparation method thereof and photochromic polyester fiber 武汉纺织大学 2021-03-12 CN disclosed