Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685900 | 0.93 | ALDH1A1 (0.64) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28910238 | 0.91 | ALDH1A1 (0.62) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28239241 | 0.89 | ALDH1A1 (0.60) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28542658 | 0.89 | ALDH1A1 (0.79) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28537086 | 0.89 | SMN1; SMN2 (0.57) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL8758318 | 0.89 | ALDH1A1 (0.76) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28910240 | 0.87 | LTB4R (0.56) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28525408 | 0.86 | ALDH1A1 (0.60) | POLBALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL28908614 | 0.85 | TP53 (0.54) | POLBALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL797463 | 0.84 | ALDH1A1 (0.69) | POLBALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | disclosed |