Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016763 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2EGLN1METAP2METAP1 | |
| SCHEMBL27490039 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2EGLN1METAP2METAP1 | |
| SCHEMBL15223622 | 0.82 | CA1 (0.39) | NPSR1MAPTCA1CA2CA7 | |
| SCHEMBL15223607 | 0.79 | CTSK (0.39) | NPSR1MAPTCA1CA2CA7 | |
| SCHEMBL7803484 | 0.79 | CYP1A2 (0.54) | SMN1; SMN2MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL14357345 | 0.79 | CYP1A2 (0.54) | SMN1; SMN2MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL15663302 | 0.79 | CYP1A2 (0.54) | SMN1; SMN2MAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL6016803 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2EGLN1MAPTHTTTDP1 | |
| SCHEMBL6016802 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2EGLN1MAPTHTTTDP1 | |
| SCHEMBL4960459 | 0.78 | MAPT (0.39) | NPSR1MAPTCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074808-B | Therapeutic compounds as orexin-1 receptor inhibitors | 希四克斯探索有限公司 | 2021-03-02 | — | — | CN | disclosed |