Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016803 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2EGLN1MMEACECPA1 | |
| SCHEMBL27490039 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2EGLN1 | |
| SCHEMBL6016763 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2EGLN1 | |
| SCHEMBL10513380 | 0.83 | TYR (0.44) | SMN1; SMN2MMEACECPA1ACE2 | |
| SCHEMBL3551870 | 0.83 | TYR (0.44) | SMN1; SMN2MMEACECPA1ACE2 | |
| SCHEMBL753926 | 0.83 | TYR (0.44) | SMN1; SMN2MMEACECPA1ACE2 | |
| SCHEMBL28396955 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL28396958 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL28802170 | 0.82 | TYR (0.43) | SMN1; SMN2MMEACECPA1ACE2 | |
| Hydrochloric Acid SCHEMBL27346770 | 0.82 | TYR (0.43) | SMN1; SMN2MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109305946-A | A kind of synthetic method of 4- methyl -5- ethyoxyl oxazole | 湖北惠生药业有限公司 | 2019-02-05 | — | — | CN | disclosed |
| EP-1611084-A1 | PROCESS FOR THE MANUFACTURE OF N-ALKOXALYL-ALANINATES | DSM IP Assets B.V. (NL) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087640-A1 | PROCESS FOR THE MANUFACTURE OF N-ALKOXALYL-ALANINATES | DSM IP ASSETS B.V. (NL) | 2004-10-14 | — | — | WO | disclosed |