Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204867 | 0.81 | L3MBTL1 (0.43) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL28904396 | 0.81 | CA1 (0.49) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL18951969 | 0.81 | CA1 (0.49) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL4170909 | 0.78 | KDM4E (0.49) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL28649703 | 0.75 | CA1 (0.44) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL28479304 | 0.75 | CA1 (0.53) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL13257984 | 0.74 | CA1 (0.49) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL2184458 | 0.74 | CA1 (0.43) | CA1CA2ALDH1A1KDM4EUBE2N | |
| SCHEMBL30625972 | 0.74 | CA1 (0.43) | CA1CA2ALDH1A1RAPGEF4KDM4E | |
| SCHEMBL28733308 | 0.73 | ALDH1A1 (0.47) | CA1CA2ALDH1A1RAPGEF4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-112638477-A | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-110637022-A | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2019-12-31 | — | — | CN | disclosed |