Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19204912 | 0.83 | L3MBTL1 (0.45) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL17397399 | 0.81 | CA1 (0.49) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL28538858 | 0.81 | CA1 (0.49) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL5795139 | 0.77 | ALDH1A1 (0.45) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL5793051 | 0.75 | L3MBTL1 (0.46) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL3360534 | 0.74 | CYP2C9 (0.41) | L3MBTL1POLBNOD1CA1CA2 | |
| SCHEMBL28733308 | 0.73 | ALDH1A1 (0.47) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL14487909 | 0.72 | ELANE (0.38) | L3MBTL1CA1CA2RAPGEF4ALDH1A1 | |
| SCHEMBL31315854 | 0.72 | KDM4E (0.46) | L3MBTL1POLBHTTALDH3A1NOD1 | |
| SCHEMBL3188642 | 0.71 | RAPGEF4 (0.61) | L3MBTL1POLBHTTALDH3A1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133664-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT， AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133667-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |