Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30325275 | 0.87 | PADI4 (0.52) | KDM4EHPGDGAAMAPTPOLB | |
| SCHEMBL25145104 | 0.87 | PADI4 (0.52) | KDM4EHPGDGAAMAPTPOLB | |
| Hydrochloric Acid SCHEMBL30325573 | 0.86 | PADI4 (0.53) | KDM4EHPGDGAAMAPTPOLB | |
| Hydrochloric Acid SCHEMBL28524626 | 0.86 | PADI4 (0.53) | KDM4EHPGDGAAMAPTPOLB | |
| SCHEMBL28539904 | 0.84 | LMNA (0.47) | KDM4EHPGDGAAMAPTALDH1A1 | |
| SCHEMBL28530840 | 0.82 | PADI4 (0.58) | PTGER4PADI4 | |
| SCHEMBL28411392 | 0.81 | ALDH1A1 (0.61) | KMT2AKDM4EHPGDGAAMAPT | |
| Hydrochloric Acid SCHEMBL28529826 | 0.81 | PADI4 (0.57) | PTGER4PADI4 | |
| SCHEMBL17431695 | 0.78 | PTGER4 (0.56) | KMT2AKDM4EHPGDMAPTPTGER4 | |
| SCHEMBL19763372 | 0.75 | CA1 (0.51) | KMT2AKDM4EHPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849015-B | Benzimidazole derivatives as PAD4 inhibitors | 葛兰素知识产权发展有限公司 | 2021-03-19 | — | — | CN | disclosed |