Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532373 | 0.82 | ALDH1A1 (0.55) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17339148 | 0.78 | ALDH1A1 (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28540023 | 0.77 | FNTA (0.55) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL8773458 | 0.76 | HCRTR1 (0.62) | KDM4EALDH1A1GLAGAACDC25B | |
| SCHEMBL6442064 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28910370 | 0.75 | FNTA (0.50) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28531366 | 0.75 | FNTA (0.48) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17339205 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL9535179 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL17339192 | 0.71 | KDM4E (0.56) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875601-A | Synthetic method and application of indolizine compound | 遵义医科大学 | 2020-11-03 | — | — | CN | disclosed |