SCHEMBL28539260

SCHEMBL28539260

CCOC(=O)C(OC(=O)c1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
MAPT P10636 5/20 0.49
POLB P06746 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
LMNA P02545 2/20 0.48
RECQL P46063 2/20 0.48
MAPK1 P28482 1/20 0.48
UBE2N P61088 1/20 0.48
HTR1E P28566 1/20 0.47
S1PR3 Q99500 1/20 0.47
UTS2R Q9UKP6 2/20 0.47
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
SIRT3 Q9NTG7 1/20 0.44
MMP8 P22894 1/20 0.43
ESR1 P03372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541441 0.90 ALDH1A1 (0.58) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28554580 0.89 LMNA (0.51) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28544691 0.89 ALDH1A1 (0.49) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28554572 0.89 NPSR1 (0.61) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28543648 0.87 ALDH1A1 (0.61) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28552028 0.87 MAPT (0.48) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28541413 0.86 ALDH1A1 (0.49) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28549184 0.85 LMNA (0.48) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28543696 0.84 ALDH1A1 (0.47) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL28278028 0.84 ALDH1A1 (0.52) ALDH1A1NPSR1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed