SCHEMBL28554580

SCHEMBL28554580

CCCOC(=O)C(OC(=O)c1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.51
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
MAPT P10636 6/20 0.47
POLB P06746 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
UTS2R Q9UKP6 1/20 0.46
ALDH1A1 P00352 8/20 0.44
NPSR1 Q6W5P4 2/20 0.44
RECQL P46063 2/20 0.44
MAPK1 P28482 1/20 0.44
UBE2N P61088 1/20 0.44
TSHR P16473 2/20 0.43
SLC6A2 P23975 2/20 0.43
ESR1 P03372 2/20 0.43
CHRM1 P11229 1/20 0.43
KDR P35968 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTR1E P28566 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552028 0.92 MAPT (0.48) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28277999 0.90 LMNA (0.63) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28539260 0.89 ALDH1A1 (0.49) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28554575 0.88 NPSR1 (0.57) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28277995 0.88 ALDH1A1 (0.56) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28539168 0.87 LMNA (0.51) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28539280 0.86 LMNA (0.48) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28548556 0.86 LMNA (0.50) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28279403 0.84 LMNA (0.48) LMNAMEN1KMT2AMAPTPOLB
SCHEMBL28278037 0.82 NPC1 (0.53) LMNAMEN1KMT2AMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN claimed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-109553705-B Catalyst component for olefin polymerization and preparation method thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-109553712-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed