Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.44 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.44 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.44 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.44 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528011 | 0.91 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28530692 | 0.86 | ABCC2 (0.60) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28238269 | 0.86 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28900519 | 0.85 | CACNB4 (0.60) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28469224 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28900440 | 0.79 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28238255 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28525489 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL28910240 | 0.75 | LTB4R (0.56) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A | |
| SCHEMBL6707621 | 0.75 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |