SCHEMBL28539601

SCHEMBL28539601

C#Cc1ccccc1OC=C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
FABP7 O15540 1/20 0.31
FABP3 P05413 1/20 0.31
FABP5 Q01469 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27536496 0.81 FABP7 (0.33) FABP7FABP3FABP5
SCHEMBL5612565 0.81 GAA (0.46) ADRA2B
SCHEMBL29592755 0.78 ADRA2B (0.43) ADRA2BADRA2C
SCHEMBL3113317 0.78 ADRA2B (0.43) ADRA2BADRA2C
SCHEMBL11243557 0.78 TRPA1 (0.32) FABP7FABP3FABP5
SCHEMBL3842879 0.77 POLB (0.39) FABP7FABP3FABP5
SCHEMBL28541058 0.76 MAPT (0.50)
SCHEMBL28799399 0.75 GRM5 (0.37) ADRA2BADRA2C
SCHEMBL28707999 0.74 THRB (0.46) FABP7FABP3FABP5
SCHEMBL236305 0.73 CA1 (0.55) ADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112442002-B Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound 桂林医学院 2022-09-20 CN claimed
CN-112442002-A Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound 桂林医学院 2021-03-05 CN claimed
CN-112442002-B Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound 桂林医学院 2022-09-20 CN disclosed
CN-112442002-B Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound 桂林医学院 2022-09-20 CN disclosed
CN-110467553-B Novel method based on nitration/cyclization reaction of 1, 6-eneyne compounds 长江师范学院 2021-05-04 CN disclosed
CN-112442002-A Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound 桂林医学院 2021-03-05 CN disclosed
CN-112442002-A Method for synthesizing 11-sulfenyl naphtho [2,3-b ] benzofuran compound 桂林医学院 2021-03-05 CN disclosed