Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640885 | 0.81 | MYC (0.43) | MEN1KMT2AHPGDTSHRMYC | |
| SCHEMBL21425206 | 0.81 | MAPT (0.50) | NAMPTP2RY14 | |
| SCHEMBL15140927 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AHPGDTSHRMYC | |
| SCHEMBL31450581 | 0.80 | LSS (0.46) | MYCNAMPTSIGMAR1TDP1 | |
| SCHEMBL28985437 | 0.80 | MYC (0.39) | MEN1KMT2ATSHRMYCCYP2C9 | |
| SCHEMBL14563065 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2AHPGDTSHRALOX15 | |
| SCHEMBL21713264 | 0.74 | PTPN1 (0.55) | MEN1KMT2ANAMPT | |
| SCHEMBL13718336 | 0.73 | ESR1 (0.52) | KIF11 | |
| SCHEMBL23577529 | 0.72 | PRMT5 (0.40) | MEN1KMT2AHPGDTSHRNAMPT | |
| SCHEMBL25243642 | 0.71 | CHRNB2 (0.62) | MEN1KMT2AHPGDMYCCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |