Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL28819973 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2ALOX5LMNAABCB1 | |
| Carbamic Acid SCHEMBL16991767 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CTSBABCB1 | |
| Carbamic Acid SCHEMBL16991750 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CTSBABCB1 | |
| SCHEMBL7720033 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CCR6PAX8CTSBHCAR2 | |
| SCHEMBL10557010 | 0.78 | ALDH1A1 (0.45) | ALDH1A1CCR6PAX8CTSBHCAR2 | |
| SCHEMBL7382333 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CCR6PAX8LMNA | |
| SCHEMBL7473612 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CCR6PAX8LMNA | |
| SCHEMBL28661362 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2CCR6PAX8CTSB | |
| SCHEMBL7715854 | 0.76 | ALDH1A1 (0.43) | ALDH1A1CCR6PAX8CTSBLMNA | |
| SCHEMBL16564957 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106163568-B | Antibody Drug Conjugates (ADC) containing spindle Kinesin (KSP) | 拜耳制药股份公司 | 2021-03-23 | — | — | CN | disclosed |