Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729965 | 0.84 | DGAT1 (0.43) | CTSKTDP1 | |
| SCHEMBL9403546 | 0.84 | DGAT1 (0.43) | CTSKTDP1 | |
| Biphenyl SCHEMBL28555154 | 0.79 | GRM6 (0.46) | GRM6CYP2C19CYP2C9HPGDSBCHE | |
| SCHEMBL22164590 | 0.77 | CYP1A2 (0.42) | GRM6CYP2C19BCHEALDH1A1LMNA | |
| SCHEMBL28549279 | 0.76 | MAPT (0.39) | GRM6CYP2C19CYP2C9USP30LMNA | |
| SCHEMBL6946381 | 0.74 | CYP2C19 (0.46) | GRM6CYP2C19CYP2C9USP30LMNA | |
| Biphenyl SCHEMBL28089702 | 0.74 | ELANE (0.46) | GRM6CYP2C19CYP2C9BCHEALDH1A1 | |
| SCHEMBL5711180 | 0.73 | SMN1; SMN2 (0.45) | CYP2C19CYP2C9ALDH1A1CA12CA1 | |
| SCHEMBL8071398 | 0.73 | SMN1; SMN2 (0.45) | CYP2C19CYP2C9ALDH1A1CA12CA1 | |
| SCHEMBL27899381 | 0.72 | ALDH1A1 (0.51) | CYP2C19CYP2C9ALDH1A1LMNACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349876-B | Substituted biphenyl compound and pharmaceutical composition thereof | 深圳市塔吉瑞生物医药有限公司 | 2021-03-02 | — | — | CN | disclosed |